|Application ||IHC-P, E|
|Dilution||ELISA (1:1000), IHC-P (10 µg/ml),|
|Other Names||Thrombopoietin, C-mpl ligand, ML, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand, THPO, MGDF|
|Target/Specificity||Amino acids 35 to 50 of human THPO|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||THPO / TPO / Thrombopoietin Antibody (aa35-50) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.|
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Provided below are standard protocols that you may find useful for product applications.
Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
de Sauvage F.J.,et al.Nature 369:533-538(1994).
Bartley T.D.,et al.Cell 77:1117-1124(1994).
Foster D.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:13023-13027(1994).
Sohma Y.,et al.FEBS Lett. 353:57-61(1994).
Gurney A.L.,et al.Blood 85:981-988(1995).
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