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SP3 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q02447 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 82kDa |
| Dilution | IHC-P (1:50) |
| Gene ID | 6670 |
|---|---|
| Other Names | Transcription factor Sp3, SPR-2, SP3 |
| Target/Specificity | Peptide mapping to the carboxy terminus of human Sp3 |
| Reconstitution & Storage | +4°C, avoid freezing |
| Precautions | SP3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SP3 |
|---|---|
| Function | Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping. |
| Cellular Location | Nucleus. Nucleus, PML body. Note=Localizes to the nuclear periphery and in nuclear dots when sumoylated. Some localization in PML nuclear bodies |
| Tissue Location | Ubiquitously expressed. |
| Volume | 50 µl |
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