|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Hamster, Monkey, Pig, Chicken, Sheep, Horse, Bovine, Guinea Pig, Dog|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Metalloproteinase inhibitor 2, CSC-21K, Tissue inhibitor of metalloproteinases 2, TIMP-2, TIMP2|
|Target/Specificity||Ovalbumin-conjugated synthetic Peptide DSGNDIYGNPI|
|Reconstitution & Storage||+4°C, avoid freezing|
|Precautions||TIMP2 Antibody (clone F27P3A4) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.|
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Provided below are standard protocols that you may find useful for product applications.
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
Stetler-Stevenson W.G.,et al.J. Biol. Chem. 265:13933-13938(1990).
Boone T.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:2800-2804(1990).
Hammani K.,et al.J. Biol. Chem. 271:25498-25505(1996).
Malik K.,et al.Submitted (AUG-1990) to the EMBL/GenBank/DDBJ databases.
Stetler-Stevenson W.G.,et al.J. Biol. Chem. 264:17374-17378(1989).
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