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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PTAR2 / FNTA Antibody (aa150-250)   

PTAR2 / FNTA Antibody (aa150-250)

Rabbit Polyclonal Antibody

     
  • WB - PTAR2 / FNTA Antibody (aa150-250) ALS11913
    Western blot of farnesyltransferase inumouse colon?cell lysate in the 1) absence and 2)...
  • IHC - PTAR2 / FNTA Antibody (aa150-250) ALS11913
    Anti-FNTA antibody IHC of human prostate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P49354
Reactivity Human, Mouse, Rat, Chicken, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 44kDa
Dilution IHC-P (10 µg/ml), WB (1-3 µg/ml),
Additional Information
Gene ID 2339
Other Names Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, 2.5.1.58, 2.5.1.59, CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha, FNTA
Target/Specificity A portion of amino acids 150-250 of human farnesyltransferase
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsPTAR2 / FNTA Antibody (aa150-250) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FNTA
Function Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
Research Areas
Citations (0)

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Background

Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.

References

Andres D.A.,et al.Genomics 18:105-112(1993).
Andres D.A.,et al.J. Biol. Chem. 268:1383-1390(1993).
Omer C.A.,et al.Biochemistry 32:5167-5176(1993).
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS11913
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