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ACSL3 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - ACSL3 Antibody (N-Terminus) ALS11948
    Anti-ACSL3 antibody IHC of human skeletal muscle.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O95573
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 80kDa
Dilution ELISA (1 µg/ml), IHC-P (20 µg/ml), WB (1 µg/ml)
Additional Information
Gene ID 2181
Other Names Long-chain-fatty-acid--CoA ligase 3, 6.2.1.3, Long-chain acyl-CoA synthetase 3, LACS 3, ACSL3, ACS3, FACL3, LACS3
Target/Specificity synthetic peptide corresponding to N-terminal residues of human FACL3(long-chain fatty-acid-Coenzyme A ligase 3)
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsACSL3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACSL3
Synonyms ACS3, FACL3, LACS3
Function Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL3 mediates hepatic lipogenesis (By similarity). Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (By similarity). Has mainly an anabolic role in energy metabolism. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins).
Cellular Location Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein
Research Areas
Citations (0)

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Background

Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL3 mediates hepatic lipogenesis (By similarity). Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (By similarity). Has mainly an anabolic role in energy metabolism. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins).

References

Minekura H.,et al.Genomics 42:180-181(1997).
Minekura H.,et al.Gene 278:185-192(2001).
Yao H.,et al.J. Biol. Chem. 283:849-854(2008).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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$ 395.00
Cat# ALS11948
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