|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml), WB (2 µg/ml),|
|Other Names||Cell division control protein 6 homolog, CDC6-related protein, Cdc18-related protein, HsCdc18, p62(cdc6), HsCDC6, CDC6, CDC18L|
|Target/Specificity||Recombinant (partial), Amino acid residues 400-500|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||CDC6 Antibody (aa400-500) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.|
|Cellular Location||Nucleus. Cytoplasm. Note=The protein is nuclear in G1 and cytoplasmic in S-phase cells (PubMed:9566895)|
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Provided below are standard protocols that you may find useful for product applications.
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
Williams R.S.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:142-147(1997).
Saha P.,et al.Mol. Cell. Biol. 18:2758-2767(1998).
Hall J.R.,et al.Mol. Biol. Cell 18:3340-3350(2007).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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