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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   HTR3A / 5-HT3A Receptor Antibody (aa21-36)   

HTR3A / 5-HT3A Receptor Antibody (aa21-36)

Rabbit Polyclonal Antibody

     
  • WB - HTR3A / 5-HT3A Receptor Antibody (aa21-36) ALS12085
    Western blot of 5-HT3R in human brain tissue lysate with anti-5-HT3R pcAb .
  • IHC - HTR3A / 5-HT3A Receptor Antibody (aa21-36) ALS12085
    Anti-5HT3A receptor antibody IHC of human heart.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P46098
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 55kDa
Dilution IHC-P (5 µg/ml), WB (1 µg/ml),
Additional Information
Gene ID 3359
Other Names 5-hydroxytryptamine receptor 3A, 5-HT3-A, 5-HT3A, 5-hydroxytryptamine receptor 3, 5-HT-3, 5-HT3R, Serotonin receptor 3A, Serotonin-gated ion channel receptor, HTR3A, 5HT3R, HTR3
Target/Specificity A mixture of synthetic peptides corresponding to amino acids 21-36 and 421-436 of rat 5-HT3 receptor
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsHTR3A / 5-HT3A Receptor Antibody (aa21-36) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HTR3A
Synonyms 5HT3R, HTR3
Function This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Cellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta.
Research Areas
Citations (0)

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Background

This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.

References

Miyake A.,et al.Mol. Pharmacol. 48:407-416(1995).
Belelli D.,et al.Mol. Pharmacol. 48:1054-1062(1995).
Bruess M.,et al.Ann. N. Y. Acad. Sci. 861:234-235(1998).
Bruess M.,et al.Neuropharmacology 39:308-315(2000).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS12085
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