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DCAF6 / NRIP Antibody (aa800-850)

Rabbit Polyclonal Antibody

     
  • WB - DCAF6 / NRIP Antibody (aa800-850) ALS12089
    Western blot of NRIP in human muscle tissue lysate in the 1) absence and 2) presence of...
    detail
  • IHC - DCAF6 / NRIP Antibody (aa800-850) ALS12089
    Anti-DCAF6 / NRIP antibody IHC of human skeletal muscle.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q58WW2
Reactivity Human, Mouse, Rat, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 96kDa
Dilution IHC-P (10 µg/ml), WB (1-3 µg/ml),
Additional Information
Gene ID 55827
Other Names DDB1- and CUL4-associated factor 6, Androgen receptor complex-associated protein, ARCAP, IQ motif and WD repeat-containing protein 1, Nuclear receptor interaction protein, NRIP, DCAF6, IQWD1
Target/Specificity A portion of amino acids 800-850 of human NRIP was used as the immunogen.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsDCAF6 / NRIP Antibody (aa800-850) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DCAF6
Synonyms IQWD1
Function Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Cellular Location Nucleus.
Tissue Location Highly expressed in skeletal muscle and testis. Expressed to a lesser degree in heart, prostate, and adrenal gland
Research Areas
Citations (0)
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Background

Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

References

Tsai T.C.,et al.J. Biol. Chem. 280:20000-20009(2005).
Chang T.-J.,et al.Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
Zhao B.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).

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Discontinued
Cat# ALS12089
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