|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Rat, Dog|
|Dilution||IHC-P (10 µg/ml), WB (1-3 µg/ml),|
|Other Names||DDB1- and CUL4-associated factor 6, Androgen receptor complex-associated protein, ARCAP, IQ motif and WD repeat-containing protein 1, Nuclear receptor interaction protein, NRIP, DCAF6, IQWD1|
|Target/Specificity||A portion of amino acids 800-850 of human NRIP was used as the immunogen.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||DCAF6 / NRIP Antibody (aa800-850) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.|
|Tissue Location||Highly expressed in skeletal muscle and testis. Expressed to a lesser degree in heart, prostate, and adrenal gland.|
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Provided below are standard protocols that you may find useful for product applications.
Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Tsai T.C.,et al.J. Biol. Chem. 280:20000-20009(2005).
Chang T.-J.,et al.Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
Zhao B.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
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