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TMEM123 / Porimin Antibody (aa173-188)

Rabbit Polyclonal Antibody

     
  • WB - TMEM123 / Porimin Antibody (aa173-188) ALS12113
    Western blot of Porimin using antibody at 2 ug/ml?dilution against 20 ug/lane of?HL60 cell lysate.
  • IHC - TMEM123 / Porimin Antibody (aa173-188) ALS12113
    Anti-TMEM123 antibody IHC of human lung.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q8N131
Reactivity Human, Rabbit, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 22kDa
Dilution IHC-P (5 µg/ml), WB (1-3 µg/ml),
Additional Information
Gene ID 114908
Other Names Porimin, Keratinocytes-associated transmembrane protein 3, KCT-3, Pro-oncosis receptor inducing membrane injury, Transmembrane protein 123, TMEM123, KCT3
Target/Specificity A synthetic peptide corresponding to amino acids 173-188 SRRGIRYRTIDEHDAI of human Porimin; GenBank no. AAG2164.1. This sequence is 100% conserved in cow, and 93% conserved in rat, mouse, and chicken.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsTMEM123 / Porimin Antibody (aa173-188) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMEM123
Synonyms KCT3
Function Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Ubiquitous. Not expressed in ovary. Expressed in keratinocytes.
Research Areas
Citations (0)

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Background

Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability.

References

Ma F.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:9778-9783(2001).
Bonkobara M.,et al.Br. J. Dermatol. 148:654-664(2003).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Otsuki T.,et al.DNA Res. 12:117-126(2005).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).

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$ 395.00
Cat# ALS12113
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