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TNFRSF13B / TACI Antibody (aa116-132)

Rabbit Polyclonal Antibody

     
  • WB - TNFRSF13B / TACI Antibody (aa116-132) ALS12132
    Western blot of 0.1 ug/ml of TACI in 10 ug/lane of Daudi lysate.
  • IHC - TNFRSF13B / TACI Antibody (aa116-132) ALS12132
    Anti-TACI antibody IHC of human spleen.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, Flo
Primary Accession O14836
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 32kDa
Dilution IHC-P (5 µg/ml), WB (5 µg/ml),
Additional Information
Gene ID 23495
Other Names Tumor necrosis factor receptor superfamily member 13B, Transmembrane activator and CAML interactor, CD267, TNFRSF13B, TACI
Target/Specificity A synthetic peptide corresponding to amino acids 116-132 of human TACI. Human and mouse TACI amino acid sequences are 65% conserved in the immunogen.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsTNFRSF13B / TACI Antibody (aa116-132) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFRSF13B
Synonyms TACI
Function Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T- cell function and the regulation of humoral immunity.
Cellular Location Membrane; Single-pass type III membrane protein
Tissue Location Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B- cells and activated T-cells, but not in resting T-cells
Volume 1 ea
Research Areas
Citations (0)

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Background

Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T- cell function and the regulation of humoral immunity.

References

von Buelow G.-U.,et al.Science 278:138-141(1997).
Zhou G.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Wu Y.,et al.J. Biol. Chem. 275:35478-35485(2000).

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$ 395.00
Cat# ALS12132
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