|Application ||WB, IHC-P, IF|
|Dilution||IHC-P (5 µg/ml), WB (2-4 µg/ml),|
|Other Names||Solute carrier family 2, facilitated glucose transporter member 1, Glucose transporter type 1, erythrocyte/brain, GLUT-1, HepG2 glucose transporter, SLC2A1, GLUT1|
|Target/Specificity||Recognizes human Glut-1.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SLC2A1 / GLUT-1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Melanosome. Note=Localizes primarily at the cell surface Identified by mass spectrometry in melanosome fractions from stage I to stage IV|
|Tissue Location||Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues|
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Provided below are standard protocols that you may find useful for product applications.
Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.
Mueckler M.,et al.Science 229:941-945(1985).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Fukumoto H.,et al.Diabetes 37:657-661(1988).
Yu W.,et al.Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
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