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DCTN1 / Dynactin 1 Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • WB - DCTN1 / Dynactin 1 Antibody (C-Terminus) ALS12191
    Antibody staining (1 ug/ml) of Human Testis lysate (RIPA buffer, 35 ug total protein per lane).
  • IHC - DCTN1 / Dynactin 1 Antibody (C-Terminus) ALS12191
    Anti-DCTN1 antibody IHC of human brain, cerebellum.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q14203
Reactivity Human, Mouse, Hamster, Monkey, Horse
Host Goat
Clonality Polyclonal
Calculated MW 142kDa
Dilution ELISA (1:128000), IHC-P (2.5 µg/ml), WB (1:128000)
Additional Information
Gene ID 1639
Other Names Dynactin subunit 1, 150 kDa dynein-associated polypeptide, DAP-150, DP-150, p135, p150-glued, DCTN1
Target/Specificity Human DCTN1. This antibody is expected to recognise all reported isoforms (NP_004073.2; NP_075408.1; NP_001128512.1; NP_001128513.1).
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsDCTN1 / Dynactin 1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DCTN1
Function Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein- dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton Note=Colocalizes with microtubules
Tissue Location Brain.
Research Areas
Citations (0)

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Background

Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein- dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.

References

Collin G.B.,et al.Genomics 53:359-364(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Holzbaur E.L.F.,et al.Genomics 31:398-399(1996).

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$ 395.00
Cat# ALS12191
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