|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Hamster, Monkey, Horse|
|Dilution||ELISA (1:128000), IHC-P (2.5 µg/ml), WB (1:128000)|
|Other Names||Dynactin subunit 1, 150 kDa dynein-associated polypeptide, DAP-150, DP-150, p135, p150-glued, DCTN1|
|Target/Specificity||Human DCTN1. This antibody is expected to recognise all reported isoforms (NP_004073.2; NP_075408.1; NP_001128512.1; NP_001128513.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||DCTN1 / Dynactin 1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein- dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton Note=Colocalizes with microtubules|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein- dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.
Collin G.B.,et al.Genomics 53:359-364(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Holzbaur E.L.F.,et al.Genomics 31:398-399(1996).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.