|Application ||WB, IHC-P, E|
|Reactivity||Human, Rabbit, Pig, Horse, Xenopus, Dog|
|Dilution||IHC-P (5 µg/ml), WB (0.25-0.5 µg/ml),|
|Other Names||Eukaryotic translation initiation factor 4E transporter, 4E-T, eIF4E transporter, Eukaryotic translation initiation factor 4E nuclear import factor 1, EIF4ENIF1|
|Target/Specificity||Human EIF4ENIF1. This antibody is expected to recognise isoform 1 (NP_062817.2) and isoform b (NP_001157974.1). Reported variants represent identical protein (NP_062817.2; NP_001157973.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||EIF4ENIF1 / 4E-T Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Nucleoplasmic shuttling protein. Mediates the nuclear import of EIF4E by a piggy-back mechanism.|
|Cellular Location||Cytoplasm. Nucleus. Nucleus, PML body. Nucleus speckle. Note=Predominantly cytoplasmic Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Localization to nuclear foci and speckles requires active transcription|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Nucleoplasmic shuttling protein. Mediates the nuclear import of EIF4E by a piggy-back mechanism.
Dostie J.,et al.EMBO J. 19:3142-3156(2000).
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham I.,et al.Nature 402:489-495(1999).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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