GCLC Antibody (aa295-313)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E, IP |
---|---|
Primary Accession | P48506 |
Reactivity | Human, Mouse, Rat, Monkey, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 73kDa |
Dilution | IHC-P (5 µg/ml) |
Gene ID | 2729 |
---|---|
Other Names | Glutamate--cysteine ligase catalytic subunit, 6.3.2.2, GCS heavy chain, Gamma-ECS, Gamma-glutamylcysteine synthetase, GCLC, GLCL, GLCLC |
Target/Specificity | Recognizes the heavy subunit of rat GCS. Species cross-reactivity: human, monkey and mouse. Cross-reacts weakly with bovine. |
Reconstitution & Storage | +4°C or -20°C, Avoid repeated freezing and thawing. |
Precautions | GCLC Antibody (aa295-313) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GCLC (HGNC:4311) |
---|---|
Synonyms | GLCL, GLCLC |
Function | Catalyzes the ATP-dependent ligation of L-glutamate and L- cysteine and participates in the first and rate-limiting step in glutathione biosynthesis. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
References
Gipp J.J.,et al.Biochem. Biophys. Res. Commun. 185:29-35(1992).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mulcahy R.T.,et al.Biochem. Biophys. Res. Commun. 209:227-233(1995).
Beutler E.,et al.Blood 94:2890-2894(1999).
Misra I.,et al.Protein Expr. Purif. 13:268-276(1998).
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