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SLC2A2 / GLUT2 Antibody

Mouse Monoclonal Antibody

     
  • IHC - SLC2A2 / GLUT2 Antibody ALS12261
    Anti-GLUT2 antibody IHC of human liver.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, ICC, Flo
Primary Accession P11168
Reactivity Human
Host Mouse
Clonality Monoclonal
Calculated MW 57kDa
Dilution ICC (10 µg/ml), IHC-P (10 µg/ml),
Additional Information
Gene ID 6514
Other Names Solute carrier family 2, facilitated glucose transporter member 2, Glucose transporter type 2, liver, GLUT-2, SLC2A2, GLUT2
Target/Specificity Recognizes human GLUT 2 (Glucose Transporter, Insulin Regulatable) expression on hGlut2-transfected NS0 cells but not on control transfectants. Detects Glut2 on the surface of the human intestinal cell line Caco2 in flow cytometry and on fixed cells ...
Reconstitution & Storage Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
PrecautionsSLC2A2 / GLUT2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC2A2
Synonyms GLUT2
Function Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Liver, insulin-producing beta cell, small intestine and kidney
Research Areas
Citations (0)

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Background

Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.

References

Fukumoto H.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:5434-5438(1988).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Matsubara A.,et al.J. Clin. Endocrinol. Metab. 80:3131-3135(1995).

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$ 395.00
Cat# ALS12261
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