|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||90647 Da|
|Dilution||ELISA (1:25000), IHC-P (20-40 µg/ml), WB (1:500-1:2000)|
|Other Names||Signal transducer and activator of transcription 5A, STAT5A, STAT5|
|Target/Specificity||A BLAST analysis was used to suggest cross-reactivity with Stat5 alpha from human, mouse and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Stat5 alpha from other sources has not been determined.|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||STAT5 A+B Antibody (phospho-Tyr694) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.|
|Cellular Location||Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation|
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