|Application ||WB, IHC-P|
|Dilution||IHC-P (2.5 µg/ml), WB (1:500),|
|Other Names||C-X-C chemokine receptor type 6, CXC-R6, CXCR-6, CDw186, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, CD186, CXCR6, BONZO, STRL33, TYMSTR|
|Target/Specificity||peptide corresponding to amino acids near the amino terminus of human Bonzo/STRL33 The sequence of this peptide differs from those of African green monkey and pig-tailed macaque by one or two amino acids, respectively,|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||CXCR6 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BONZO, STRL33, TYMSTR|
|Function||Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in lymphoid tissues and activated T cells|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.
Deng H.K.,et al.Nature 388:296-300(1997).
Liao F.,et al.J. Exp. Med. 185:2015-2023(1997).
Loetscher M.,et al.Curr. Biol. 7:652-660(1997).
An P.,et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
Kopatz S.A.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
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