RAPSN Antibody (aa399-412)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q13702 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 46kDa |
Dilution | IHC-P (10-20 µg/ml), WB (1 µg/ml), |
Gene ID | 5913 |
---|---|
Other Names | 43 kDa receptor-associated protein of the synapse, RAPsyn, 43 kDa postsynaptic protein, Acetylcholine receptor-associated 43 kDa protein, RING finger protein 205, RAPSN, RNF205 |
Target/Specificity | Synthetic peptide corresponding to C-terminal residues of human RAPSN(43 kD receptor-associated protein of the synapse). |
Reconstitution & Storage | +4°C or -20°C, Avoid repeated freezing and thawing. |
Precautions | RAPSN Antibody (aa399-412) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RAPSN |
---|---|
Synonyms | RNF205 |
Function | Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. |
Cellular Location | Cell membrane; Peripheral membrane protein; Cytoplasmic side. Postsynaptic cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=Cytoplasmic surface of postsynaptic membranes |
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Provided below are standard protocols that you may find useful for product applications.
Background
Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin.
References
Buckel A.,et al.Genomics 35:613-616(1996).
Ohno K.,et al.Am. J. Hum. Genet. 70:875-885(2002).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Nam S.,et al.J. Biol. Chem. 284:8195-8206(2009).
Dunne V.,et al.J. Hum. Genet. 48:204-207(2003).
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