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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   TEM1 / CD248 Antibody (C-Terminus)   

TEM1 / CD248 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - TEM1 / CD248 Antibody (C-Terminus) ALS12412
    Immunofluorescence of TEM1 in Human Colon cells with TEM1 antibody at 20 ug/ml.
  • IHC - TEM1 / CD248 Antibody (C-Terminus) ALS12412
    Anti-TEM1 antibody IHC of human pancreas.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q9HCU0
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 81kDa
Dilution IHC-P (5 µg/ml), WB (0.5-1 µg/ml),
Additional Information
Gene ID 57124
Other Names Endosialin, Tumor endothelial marker 1, CD248, CD248, CD164L1, TEM1
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsTEM1 / CD248 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD248
Synonyms CD164L1, TEM1
Function May play a role in tumor angiogenesis.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts
Research Areas
Citations (0)

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Background

May play a role in tumor angiogenesis.

References

St Croix B.,et al.Science 289:1197-1202(2000).
Christian S.,et al.J. Biol. Chem. 276:7408-7414(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Rettig W.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:10832-10836(1992).
Dolznig H.,et al.Cancer Immun. 5:10-10(2005).

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$ 395.00
Cat# ALS12412
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