|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (5 µg/ml), WB (0.5-1 µg/ml),|
|Other Names||Endosialin, Tumor endothelial marker 1, CD248, CD248, CD164L1, TEM1|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||TEM1 / CD248 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in tumor angiogenesis.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
May play a role in tumor angiogenesis.
St Croix B.,et al.Science 289:1197-1202(2000).
Christian S.,et al.J. Biol. Chem. 276:7408-7414(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Rettig W.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:10832-10836(1992).
Dolznig H.,et al.Cancer Immun. 5:10-10(2005).
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