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ORAI3 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, ICC, E |
|---|---|
| Primary Accession | Q9BRQ5 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 31kDa |
| Dilution | ICC (5 µg/ml), IHC-P (3 µg/ml), WB (2-4 µg/ml) |
| Gene ID | 93129 |
|---|---|
| Other Names | Protein orai-3, Transmembrane protein 142C, ORAI3, TMEM142C |
| Target/Specificity | a 19 amino acid peptide from near the carboxy terminus of human ORAI3 |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | ORAI3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ORAI3 |
|---|---|
| Synonyms | TMEM142C |
| Function | Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in both naive and effector T helper cells with higher levels in effector cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Key regulator or component of store-operated Ca(2+) channel and transcription factor NFAT nuclear import.
References
Feske S.,et al.Nature 441:179-185(2006).
Srikanth S.,et al.Nat. Cell Biol. 12:436-446(2010).
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