|Application ||WB, IHC-P, IF, E|
|Dilution||IHC-P (3 µg/ml), WB (2-5 µg/ml),|
|Other Names||Tumor necrosis factor receptor superfamily member 17, B-cell maturation protein, CD269, TNFRSF17, BCM, BCMA|
|Target/Specificity||synthetic peptide mapping at the carboxy terminus of human BCMA|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||TNFRSF17 / BCMA Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.|
|Cellular Location||Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Note=Perinuclear Golgi-like structures|
|Tissue Location||Expressed in mature B-cells, but not in T- cells or monocytes|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Laabi Y.,et al.EMBO J. 11:3897-3904(1992).
Laabi Y.,et al.Nucleic Acids Res. 22:1147-1154(1994).
Kawasaki A.,et al.Genes Immun. 2:276-279(2001).
Smirnova A.S.,et al.Mol. Immunol. 45:1179-1183(2008).
Maia S.,et al.Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
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