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TNFRSF17 / BCMA Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - TNFRSF17 / BCMA Antibody (C-Terminus) ALS12428
    Immunofluorescence of BCMA in Human Spleen cells with BCMA antibody at 10 ug/ml.
    detail
  • IHC - TNFRSF17 / BCMA Antibody (C-Terminus) ALS12428
    Anti-BCMA antibody IHC of human colon.
    detail
  • WB - TNFRSF17 / BCMA Antibody (C-Terminus) ALS12428
    Western blot of BCMA in human spleen (A) tissue lysate, K562 (B), and U937 (C) cell lysates with...
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q02223
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 20kDa
Dilution IHC-P (3 µg/ml), WB (2-5 µg/ml),
Additional Information
Gene ID 608
Other Names Tumor necrosis factor receptor superfamily member 17, B-cell maturation protein, CD269, TNFRSF17, BCM, BCMA
Target/Specificity synthetic peptide mapping at the carboxy terminus of human BCMA
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsTNFRSF17 / BCMA Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFRSF17
Synonyms BCM, BCMA
Function Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Cellular Location Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein Note=Perinuclear Golgi-like structures
Tissue Location Expressed in mature B-cells, but not in T-cells or monocytes
Research Areas
Citations (0)
citation

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Background

Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.

References

Laabi Y.,et al.EMBO J. 11:3897-3904(1992).
Laabi Y.,et al.Nucleic Acids Res. 22:1147-1154(1994).
Kawasaki A.,et al.Genes Immun. 2:276-279(2001).
Smirnova A.S.,et al.Mol. Immunol. 45:1179-1183(2008).
Maia S.,et al.Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.

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Discontinued
Cat# ALS12428
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