|Application ||WB, IHC-P, IF, E|
|Dilution||IHC-P (3 µg/ml), WB (2-5 µg/ml),|
|Other Names||Tumor necrosis factor receptor superfamily member 17, B-cell maturation protein, CD269, TNFRSF17, BCM, BCMA|
|Target/Specificity||synthetic peptide mapping at the carboxy terminus of human BCMA|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||TNFRSF17 / BCMA Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.|
|Cellular Location||Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Note=Perinuclear Golgi-like structures|
|Tissue Location||Expressed in mature B-cells, but not in T- cells or monocytes|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Laabi Y.,et al.EMBO J. 11:3897-3904(1992).
Laabi Y.,et al.Nucleic Acids Res. 22:1147-1154(1994).
Kawasaki A.,et al.Genes Immun. 2:276-279(2001).
Smirnova A.S.,et al.Mol. Immunol. 45:1179-1183(2008).
Maia S.,et al.Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
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