AIFM3 Antibody (Internal)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q96NN9 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 67kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 150209 |
---|---|
Other Names | Apoptosis-inducing factor 3, 1.-.-.-, Apoptosis-inducing factor-like protein, AIFM3, AIFL |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | AIFM3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AIFM3 |
---|---|
Synonyms | AIFL |
Function | Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential. |
Cellular Location | Mitochondrion. Note=Does not translocate to the nucleus upon induction of apoptosis |
Tissue Location | Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
References
Xie Q.,et al.J. Biol. Chem. 280:19673-19681(2005).
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham I.,et al.Nature 402:489-495(1999).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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