|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Apoptosis-inducing factor 3, 1.-.-.-, Apoptosis-inducing factor-like protein, AIFM3, AIFL|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||AIFM3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.|
|Cellular Location||Mitochondrion. Note=Does not translocate to the nucleus upon induction of apoptosis|
|Tissue Location||Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
Xie Q.,et al.J. Biol. Chem. 280:19673-19681(2005).
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham I.,et al.Nature 402:489-495(1999).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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