|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Hamster, Monkey, Horse, Bovine, Dog|
|Dilution||IHC-P (2.5 µg/ml), WB (1:500-1:1000),|
|Other Names||Protein FAM188A, Dermal papilla-derived protein 5, Protein CARP, FAM188A, C10orf97, CARP, DERP5|
|Target/Specificity||Residues 59-76 AFLLKKLLFSSEKSSWRD of human CARP protein|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||FAM188A / C10orf97 Antibody (aa59-76) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C10orf97, CARP, DERP5|
|Function||Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. May have pro-apoptotic function. Overexpression significantly inhibits cell proliferation in several tumor cell lines.|
|Tissue Location||Highly expressed in heart, skeletal muscle, and kidney, with weak expression in liver and brain|
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May have pro-apoptotic function. Overexpression significantly inhibits cell proliferation in several tumor cell lines.
Liu B.,et al.Biochem. Biophys. Res. Commun. 293:1396-1404(2002).
Ikeda A.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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