TRIM3 Antibody (N-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, E |
---|---|
Primary Accession | O75382 |
Reactivity | Human, Mouse, Rat, Rabbit, Hamster, Monkey, Horse, Bovine, Dog |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 81kDa |
Dilution | ELISA (1:64000), IHC-P (5 µg/ml), WB (0.1-1 µg/ml) |
Gene ID | 10612 |
---|---|
Other Names | Tripartite motif-containing protein 3, Brain-expressed RING finger protein, RING finger protein 22, RING finger protein 97, TRIM3, BERP, RNF22, RNF97 |
Target/Specificity | Human TRIM3. Both variants (NP_006449.2; NP_150594.2;) represent the same protein. This antibody is expected to recognise all three human isoforms of this protein. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | TRIM3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TRIM3 |
---|---|
Synonyms | BERP, RNF22, RNF97 |
Function | Probably involved in vesicular trafficking via its association with the CART complex (PubMed:15772161). The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161). Positively regulates motility of microtubule-dependent motor protein KIF21B (By similarity). |
Cellular Location | Cytoplasm. Early endosome. Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q9R1R2}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9R1R2} |
Tissue Location | Expressed in brain, heart, uterus and testis. |

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abgent.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
References
El-Husseini A.E.-D.,et al.Genomics 71:363-367(2001).
Reymond A.,et al.EMBO J. 20:2140-2151(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.