|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Hamster, Monkey, Horse, Bovine, Dog|
|Dilution||ELISA (1:64000), IHC-P (5 µg/ml), WB (0.1-1 µg/ml)|
|Other Names||Tripartite motif-containing protein 3, Brain-expressed RING finger protein, RING finger protein 22, RING finger protein 97, TRIM3, BERP, RNF22, RNF97|
|Target/Specificity||Human TRIM3. Both variants (NP_006449.2; NP_150594.2;) represent the same protein. This antibody is expected to recognise all three human isoforms of this protein.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||TRIM3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BERP, RNF22, RNF97|
|Function||Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.|
|Cellular Location||Cytoplasm. Early endosome|
|Tissue Location||Expressed in brain, heart, uterus and testis.|
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Provided below are standard protocols that you may find useful for product applications.
Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
El-Husseini A.E.-D.,et al.Genomics 71:363-367(2001).
Reymond A.,et al.EMBO J. 20:2140-2151(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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