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The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.TRIM3 Antibody (N-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | O75382 |
| Reactivity | Human, Mouse, Rat, Rabbit, Hamster, Monkey, Horse, Bovine, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 81kDa |
| Dilution | ELISA (1:64000), IHC-P (5 µg/ml), WB (0.1-1 µg/ml) |
| Gene ID | 10612 |
|---|---|
| Other Names | Tripartite motif-containing protein 3, Brain-expressed RING finger protein, RING finger protein 22, RING finger protein 97, TRIM3, BERP, RNF22, RNF97 |
| Target/Specificity | Human TRIM3. Both variants (NP_006449.2; NP_150594.2;) represent the same protein. This antibody is expected to recognise all three human isoforms of this protein. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | TRIM3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRIM3 |
|---|---|
| Synonyms | BERP, RNF22, RNF97 |
| Function | Probably involved in vesicular trafficking via its association with the CART complex (PubMed:15772161). The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161). Positively regulates motility of microtubule-dependent motor protein KIF21B (By similarity). |
| Cellular Location | Cytoplasm. Early endosome. Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q9R1R2}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9R1R2} |
| Tissue Location | Expressed in brain, heart, uterus and testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
References
El-Husseini A.E.-D.,et al.Genomics 71:363-367(2001).
Reymond A.,et al.EMBO J. 20:2140-2151(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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