|Application ||WB, IHC-P, E|
|Reactivity||Human, Rabbit, Monkey, Pig, Horse, Bovine, Guinea Pig|
|Dilution||ELISA (1:32000), IHC-P (5 µg/ml), WB (1-3 µg/ml)|
|Other Names||Amine oxidase [flavin-containing] B, 22.214.171.124, Monoamine oxidase type B, MAO-B, MAOB|
|Target/Specificity||Human MAOB. This antibody is not expected to cross-react with MAOA.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||MAOB / Monoamine Oxidase B Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.|
|Cellular Location||Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side|
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Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
Grimsby J.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:3637-3641(1991).
Bach A.W.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:4934-4938(1988).
Chen K.,et al.J. Neurochem. 61:187-190(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
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