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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   SNCG / Gamma-Synuclein Antibody   

SNCG / Gamma-Synuclein Antibody

Rabbit Polyclonal Antibody

     
  • IHC - SNCG / Gamma-Synuclein Antibody ALS12582
    Anti-SNCG antibody IHC of human brain, cerebellum.
  • IHC - SNCG / Gamma-Synuclein Antibody ALS12582
    Anti-SNCG antibody IHC of human breast.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O76070
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 13kDa
Dilution IHC-P (5 µg/ml), WB (1:500-1:2000),
Additional Information
Gene ID 6623
Other Names Gamma-synuclein, Breast cancer-specific gene 1 protein, Persyn, Synoretin, SR, SNCG, BCSG1, PERSYN, PRSN
Target/Specificity This antibody is specific for gamma-synuclein and does not cross-react with alpha- and beta-synuclein.
Reconstitution & Storage Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
PrecautionsSNCG / Gamma-Synuclein Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNCG
Synonyms BCSG1, PERSYN, PRSN
Function Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).
Cellular Location Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle
Tissue Location Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung
Research Areas
Citations (0)

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Background

Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).

References

Ji H.,et al.Cancer Res. 57:759-764(1997).
Ninkina N.N.,et al.Hum. Mol. Genet. 7:1417-1424(1998).
Lavedan C.,et al.Hum. Genet. 103:106-112(1998).
Han C.,et al.Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
Pronin A.N.,et al.J. Biol. Chem. 275:26515-26522(2000).

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$ 395.00
Cat# ALS12582
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