|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Zebrafish, Monkey, Xenopus|
|Dilution||ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.5-1.5 µg/ml)|
|Other Names||Forkhead box protein C1, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3, FREAC-3, FOXC1, FKHL7, FREAC3|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||FOXC1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Regulates FOXO1 through binding to a conserved element, 5'- GTAAACAAA-3' in its promoter region, implicating FOXC1 as an important regulator of cell viability and resistance to oxidative stress in the eye.|
|Tissue Location||Expressed in all tissues and cell lines examined.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Regulates FOXO1 through binding to a conserved element, 5'- GTAAACAAA-3' in its promoter region, implicating FOXC1 as an important regulator of cell viability and resistance to oxidative stress in the eye.
Nishimura D.Y.,et al.Nat. Genet. 19:140-147(1998).
Mears A.J.,et al.Am. J. Hum. Genet. 63:1316-1328(1998).
Komatireddy S.,et al.Mol. Vis. 9:43-48(2003).
Mungall A.J.,et al.Nature 425:805-811(2003).
Hromas R.,et al.Blood 81:2854-2859(1993).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.