|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:32000), IHC-P (3 µg/ml), WB (0.5-1 µg/ml)|
|Other Names||Fanconi anemia group G protein, Protein FACG, DNA repair protein XRCC9, FANCG, XRCC9|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||FANCG Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.|
|Cellular Location||Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic|
|Tissue Location||Highly expressed in testis and thymus. Found in lymphoblasts|
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Provided below are standard protocols that you may find useful for product applications.
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
Liu N.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:9232-9237(1997).
De Winter J.P.,et al.Nat. Genet. 20:281-283(1998).
Humphray S.J.,et al.Nature 429:369-374(2004).
Garcia-Higuera I.,et al.Mol. Cell. Biol. 19:4866-4873(1999).
Meetei A.R.,et al.Mol. Cell. Biol. 23:3417-3426(2003).
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