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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   AMID / AIFM2 Antibody (N-Terminus)   

AMID / AIFM2 Antibody (N-Terminus)

Goat Polyclonal Antibody

     
  • IHC - AMID / AIFM2 Antibody (N-Terminus) ALS12602
    Anti-AIFM2 / AMID antibody IHC of human heart.
  • IHC - AMID / AIFM2 Antibody (N-Terminus) ALS12602
    Anti-AIFM2 / AMID antibody IHC of human skeletal muscle.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q9BRQ8
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 41kDa
Dilution ELISA (1:128000), IHC-P (4 µg/ml),
Additional Information
Gene ID 84883
Other Names Apoptosis-inducing factor 2, 1.-.-.-, Apoptosis-inducing factor homologous mitochondrion-associated inducer of death, Apoptosis-inducing factor-like mitochondrion-associated inducer of death, p53-responsive gene 3 protein, AIFM2, AMID, PRG3 {ECO:0000303|PubMed:12135761}
Target/Specificity Human AIFM2 / AMID.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsAMID / AIFM2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AIFM2
Synonyms AMID, PRG3 {ECO:0000303|PubMed:12135761}
Function Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest.
Cellular Location Cytoplasm. Mitochondrion outer membrane. Membrane; Lipid-anchor
Tissue Location Detected in most normal tissues as two transcripts of 1.8 and 4.0 kb in length, respectively. Highly expressed in heart, moderately in liver and skeletal muscles, and expressed at low levels in placenta, lung, kidney, and pancreas Both transcripts expressed following p53/TP53 induction. The shorter 1.8 kb transcript seems to be the major transcript in EB1 colon cancer cells.
Research Areas
Citations (0)

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Background

Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest.

References

Ohiro Y.,et al.FEBS Lett. 524:163-171(2002).
Wu M.,et al.J. Biol. Chem. 277:25617-25623(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS12602
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