|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:128000), IHC-P (5 µg/ml), WB (0.3-1 µg/ml)|
|Other Names||Sn1-specific diacylglycerol lipase alpha, DGL-alpha, 3.1.1.-, Neural stem cell-derived dendrite regulator, DAGLA, C11orf11, KIAA0659, NSDDR|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||DAGLA Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C11orf11, KIAA0659, NSDDR|
|Function||Catalyzes the hydrolysis of diacylglycerol (DAG) to 2- arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Highly expressed in brain and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the hydrolysis of diacylglycerol (DAG) to 2- arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses.
Horiguchi S.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
Ishikawa K.,et al.DNA Res. 5:169-176(1998).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bisogno T.,et al.J. Cell Biol. 163:463-468(2003).
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