|Application ||WB, IHC-P, IF, E|
|Dilution||IHC-P (2.5 µg/ml)|
|Other Names||Thymic stromal lymphopoietin, TSLP|
|Target/Specificity||19 amino acid peptide from near the center of human TSLP.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||TSLP Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Isoform 1: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.|
|Tissue Location||Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands It is secreted into saliva.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Isoform 1: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.
Reche P.A.,et al.J. Immunol. 167:336-343(2001).
Quentmeier H.,et al.Leukemia 15:1286-1292(2001).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Allakhverdi Z.,et al.J. Exp. Med. 204:253-258(2007).
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