|Application ||WB, IHC-P, IF, E|
|Dilution||IHC-P (2.5 µg/ml)|
|Other Names||Thymic stromal lymphopoietin, TSLP|
|Target/Specificity||19 amino acid peptide from near the center of human TSLP.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||TSLP Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Isoform 1: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.|
|Tissue Location||Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands It is secreted into saliva.|
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Provided below are standard protocols that you may find useful for product applications.
Isoform 1: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.
Reche P.A.,et al.J. Immunol. 167:336-343(2001).
Quentmeier H.,et al.Leukemia 15:1286-1292(2001).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Allakhverdi Z.,et al.J. Exp. Med. 204:253-258(2007).
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