|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Hamster, Monkey, Horse, Dog|
|Dilution||ELISA (1:32000), IHC-P (3.75 µg/ml), WB (1:32000)|
|Other Names||Ankyrin repeat and BTB/POZ domain-containing protein 1, Elongation factor 1A-binding protein, ABTB1 (HGNC:18275)|
|Target/Specificity||Human ABTB1 / BPOZ. This antibody is expected to recognise all reported isoforms (NP_115937.1; NP_742024.1; NP_742025.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||BPOZ / ABTB1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.|
|Tissue Location||Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart|
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Provided below are standard protocols that you may find useful for product applications.
May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.
Dai K.-S.,et al.Biochem. Biophys. Res. Commun. 273:991-996(2000).
Unoki M.,et al.Oncogene 20:4457-4465(2001).
Wan D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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