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PEBP1 / RKIP Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • WB - PEBP1 / RKIP Antibody (C-Terminus) ALS12707
    Antibody staining (0.01 ug/ml) of A549 lysate (RIPA buffer, 35 ug total protein per lane).
    detail
  • IHC - PEBP1 / RKIP Antibody (C-Terminus) ALS12707
    Anti-PEBP1 antibody IHC of human prostate.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P30086
Reactivity Human, Mouse, Hamster, Monkey, Pig, Chicken, Horse, Bovine
Host Goat
Clonality Polyclonal
Calculated MW 21kDa
Dilution ELISA (1:16000), IHC-P (1.5 µg/ml), WB (1:16000)
Additional Information
Gene ID 5037
Other Names Phosphatidylethanolamine-binding protein 1, PEBP-1, HCNPpp, Neuropolypeptide h3, Prostatic-binding protein, Raf kinase inhibitor protein, RKIP, Hippocampal cholinergic neurostimulating peptide, HCNP, PEBP1, PBP, PEBP
Target/Specificity Human PEBP1.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsPEBP1 / RKIP Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PEBP1
Synonyms PBP, PEBP
Function Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.
Cellular Location Cytoplasm.
Research Areas
Citations (0)
citation

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Background

Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.

References

Hori N.,et al.Gene 140:293-294(1994).
Tohdoh N.,et al.Brain Res. Mol. Brain Res. 30:381-384(1995).
Hall L.,et al.Submitted (FEB-1995) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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Discontinued
Cat# ALS12707
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