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IRF6 Antibody (C-Terminus)
Goat Polyclonal Antibody
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- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | O14896 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 53kDa |
| Dilution | IHC-P (2.5 µg/ml), WB (0.2-1 µg/ml), |
| Gene ID | 3664 |
|---|---|
| Other Names | Interferon regulatory factor 6, IRF-6, IRF6 |
| Target/Specificity | Human IRF6. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | IRF6 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IRF6 |
|---|---|
| Function | Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity). |
| Cellular Location | Nucleus. Cytoplasm Note=Translocates to nucleus in response to an activating signal |
| Tissue Location | Expressed in normal mammary epithelial cells. Expression is reduced or absent in breast carcinomas |
Research Areas
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