PEBP1 / RKIP Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P30086 |
Reactivity | Human, Rabbit, Monkey, Pig, Bovine, Dog |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 21kDa |
Dilution | ELISA (1:128000), IHC-P (2.5 µg/ml), WB (1:128000) |
Gene ID | 5037 |
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Other Names | Phosphatidylethanolamine-binding protein 1, PEBP-1, HCNPpp, Neuropolypeptide h3, Prostatic-binding protein, Raf kinase inhibitor protein, RKIP, Hippocampal cholinergic neurostimulating peptide, HCNP, PEBP1, PBP, PEBP |
Target/Specificity | Human PEBP1. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | PEBP1 / RKIP Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PEBP1 |
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Synonyms | PBP, PEBP |
Function | Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. |
Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.
References
Hori N.,et al.Gene 140:293-294(1994).
Tohdoh N.,et al.Brain Res. Mol. Brain Res. 30:381-384(1995).
Hall L.,et al.Submitted (FEB-1995) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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