YWHAH / 14-3-3 Eta Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q04917 |
Reactivity | Human, Mouse, Rat, Rabbit, Chicken, Sheep, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 28kDa |
Dilution | IHC-P (1:250) |
Gene ID | 7533 |
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Other Names | 14-3-3 protein eta, Protein AS1, YWHAH, YWHA1 |
Target/Specificity | Recognizes 14-3-3 eta in all mammals. It is a member of the 14-3-3 family which consists of 30 kD proteins that are involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, ... |
Reconstitution & Storage | +4°C or -20°C, Avoid repeated freezing and thawing. |
Precautions | YWHAH / 14-3-3 Eta Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | YWHAH |
---|---|
Synonyms | YWHA1 |
Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1. |
Tissue Location | Expressed mainly in the brain and present in other tissues albeit at lower levels |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
References
Swanson K.D.,et al.Biochim. Biophys. Acta 1216:145-148(1993).
Ichimura-Ohshima Y.,et al.J. Neurosci. Res. 31:600-605(1992).
Leffers H.,et al.Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.
Muratake T.,et al.Mol. Neurobiol. 11:223-230(1995).
Muratake T.,et al.Genomics 36:63-69(1996).
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