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Complement C6 Antibody (C-Terminus, clone 056B-214.2.4.2)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, E, FC |
|---|---|
| Primary Accession | P13671 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 056B-214.2.4.2 |
| Calculated MW | 105kDa |
| Dilution | IHC-P (10 µg/ml) |
| Gene ID | 729 |
|---|---|
| Other Names | Complement component C6, C6 |
| Target/Specificity | Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complemen ... |
| Reconstitution & Storage | +4°C or -20°C, Avoid repeated freezing and thawing. Store undiluted. |
| Precautions | Complement C6 Antibody (C-Terminus, clone 056B-214.2.4.2) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | C6 |
|---|---|
| Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. |
| Cellular Location | Secreted. |
| Volume | 250 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
References
Haefliger J.-A.,et al.J. Biol. Chem. 264:18041-18051(1989).
Discipio R.G.,et al.J. Biol. Chem. 264:16197-16206(1989).
Hobart M.J.,et al.Biochemistry 32:6198-6205(1993).
Soejima M.,et al.Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Schmutz J.,et al.Nature 431:268-274(2004).
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