|Application ||IHC-P, E, Flo|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Complement component C6, C6|
|Target/Specificity||Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complemen ...|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing. Store undiluted.|
|Precautions||Complement C6 Antibody (C-Terminus, clone 056B-188.8.131.52) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.|
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Provided below are standard protocols that you may find useful for product applications.
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
Haefliger J.-A.,et al.J. Biol. Chem. 264:18041-18051(1989).
Discipio R.G.,et al.J. Biol. Chem. 264:16197-16206(1989).
Hobart M.J.,et al.Biochemistry 32:6198-6205(1993).
Soejima M.,et al.Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Schmutz J.,et al.Nature 431:268-274(2004).
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