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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   FAP-1 / PTPN13 Antibody (aa2290-2491)   

FAP-1 / PTPN13 Antibody (aa2290-2491)

Rabbit Polyclonal Antibody

     
  • IHC - FAP-1 / PTPN13 Antibody (aa2290-2491) ALS12757
    Anti-PTPN13 antibody IHC of human brain, cortex.
  • IHC - FAP-1 / PTPN13 Antibody (aa2290-2491) ALS12757
    Anti-PTPN13 antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q12923
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 277kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 5783
Other Names Tyrosine-protein phosphatase non-receptor type 13, 3.1.3.48, Fas-associated protein-tyrosine phosphatase 1, FAP-1, PTP-BAS, Protein-tyrosine phosphatase 1E, PTP-E1, hPTPE1, Protein-tyrosine phosphatase PTPL1, PTPN13, PNP1, PTP1E, PTPL1
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsFAP-1 / PTPN13 Antibody (aa2290-2491) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTPN13
Synonyms PNP1, PTP1E, PTPL1
Function Tyrosine phosphatase which regulates negatively FAS- induced apoptosis and NGFR-mediated pro-apoptotic signaling (PubMed:15611135). May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 (PubMed:23604317).
Cellular Location Cytoplasm, cytoskeleton. Nucleus. Cell projection, lamellipodium. Note=Colocalizes with PKN2 in lamellipodia-like structure, regions of large actin turnover
Tissue Location Present in most tissues with the exception of the liver and skeletal muscle. Most abundant in lung, kidney and fetal brain
Research Areas
Citations (0)

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Background

Tyrosine phosphatase which regulates negatively FAS- induced apoptosis and NGFR-mediated pro-apoptotic signaling (PubMed:15611135). May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 (PubMed:23604317).

References

Banville D.,et al.J. Biol. Chem. 269:22320-22327(1994).
Maekawa K.,et al.FEBS Lett. 337:200-206(1994).
Saras J.,et al.J. Biol. Chem. 269:24082-24089(1994).
Wang H.-Y.,et al.Submitted (JUN-1994) to the EMBL/GenBank/DDBJ databases.
Sato T.,et al.Science 268:411-415(1995).

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$ 395.00
Cat# ALS12757
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