|Dilution||IHC-P (10 µg/ml)|
|Other Names||Tyrosine-protein phosphatase non-receptor type 13, 22.214.171.124, Fas-associated protein-tyrosine phosphatase 1, FAP-1, PTP-BAS, Protein-tyrosine phosphatase 1E, PTP-E1, hPTPE1, Protein-tyrosine phosphatase PTPL1, PTPN13, PNP1, PTP1E, PTPL1|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FAP-1 / PTPN13 Antibody (aa2290-2491) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||PNP1, PTP1E, PTPL1|
|Function||Tyrosine phosphatase which regulates negatively FAS- induced apoptosis and NGFR-mediated pro-apoptotic signaling (PubMed:15611135). May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 (PubMed:23604317).|
|Cellular Location||Cytoplasm, cytoskeleton. Nucleus. Cell projection, lamellipodium Note=Colocalizes with F-actin (PubMed:10826496). Colocalizes with PKN2 in lamellipodia-like structure, regions of large actin turnover (PubMed:11356191).|
|Tissue Location||Present in most tissues with the exception of the liver and skeletal muscle. Most abundant in lung, kidney and fetal brain|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Tyrosine phosphatase which regulates negatively FAS- induced apoptosis and NGFR-mediated pro-apoptotic signaling (PubMed:15611135). May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 (PubMed:23604317).
Banville D.,et al.J. Biol. Chem. 269:22320-22327(1994).
Maekawa K.,et al.FEBS Lett. 337:200-206(1994).
Saras J.,et al.J. Biol. Chem. 269:24082-24089(1994).
Wang H.-Y.,et al.Submitted (JUN-1994) to the EMBL/GenBank/DDBJ databases.
Sato T.,et al.Science 268:411-415(1995).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.