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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   P40PHOX / NCF4 Antibody (Internal)   

P40PHOX / NCF4 Antibody (Internal)

Goat Polyclonal Antibody

     
  • WB - P40PHOX / NCF4 Antibody (Internal) ALS12863
    Antibody (0.5 ug/ml) staining of Daudi cell lysate (35 ug protein in RIPA buffer).
  • IHC - P40PHOX / NCF4 Antibody (Internal) ALS12863
    Anti-NCF4 antibody IHC of human spleen.
  • IHC - P40PHOX / NCF4 Antibody (Internal) ALS12863
    Anti-NCF4 antibody IHC of human tonsil.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q15080
Reactivity Human, Monkey, Horse
Host Goat
Clonality Polyclonal
Calculated MW 39kDa
Dilution ELISA (1:32000), IHC-P (2.5 µg/ml), WB (1:32000)
Additional Information
Gene ID 4689
Other Names Neutrophil cytosol factor 4, NCF-4, Neutrophil NADPH oxidase factor 4, SH3 and PX domain-containing protein 4, p40-phox, p40phox, NCF4, SH3PXD4
Target/Specificity Human NCF4. This antibody is expected to recognise both reported isoforms (NP_000622.2 and NP_038202.1).
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsP40PHOX / NCF4 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NCF4
Synonyms SH3PXD4
Function Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. It may be important for the assembly and/or activation of the NADPH-oxidase complex.
Cellular Location Cytoplasm, cytosol. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Membrane; Peripheral membrane protein
Tissue Location Expression is restricted to hematopoietic cells
Research Areas
Citations (0)

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Background

Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. It may be important for the assembly and/or activation of the NADPH-oxidase complex.

References

Wientjes F.B.,et al.Biochem. J. 296:557-561(1993).
Zhan S.,et al.Blood 88:2714-2721(1996).
Hasebe T.,et al.FEBS Lett. 455:257-261(1999).
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS12863
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