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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   F13A1 / Factor XIIIa Antibody   

F13A1 / Factor XIIIa Antibody

Goat Polyclonal Antibody

     
  • IHC - F13A1 / Factor XIIIa Antibody ALS12918
    Anti-F13A1 / Factor XIIIa antibody IHC of human placenta.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession P00488
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 83kDa
Dilution IHC-P (3-6 µg/ml)
Additional Information
Gene ID 2162
Other Names Coagulation factor XIII A chain, Coagulation factor XIIIa, 2.3.2.13, Protein-glutamine gamma-glutamyltransferase A chain, Transglutaminase A chain, F13A1, F13A
Target/Specificity Human F13A1 / Factor XIIIa.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsF13A1 / Factor XIIIa Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name F13A1
Synonyms F13A
Function Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Cellular Location Cytoplasm. Secreted. Note=Secreted into the blood plasma Cytoplasmic in most tissues, but also secreted in the blood plasma
Research Areas
Citations (0)

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Background

Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

References

Ichinose A.,et al.Biochemistry 25:6900-6906(1986).
Grundmann U.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8024-8028(1986).
Ichinose A.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:5829-5833(1988).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).

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$ 395.00
Cat# ALS12918
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