|Application ||IHC-P, E|
|Dilution||IHC-P (3-6 µg/ml)|
|Other Names||Paired immunoglobulin-like type 2 receptor beta, Activating receptor PILR-beta, Cell surface receptor FDFACT, PILRB, FDFACT|
|Target/Specificity||Human PILRB. Both variants represent identical proteins (NP_038468.3; NP_839956.1). This antibody is expected to recognize isoform a only (NP_038468.3; NP_839956.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||PILRB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface.
Mousseau D.D.,et al.J. Biol. Chem. 275:4467-4474(2000).
Bates E.E.,et al.Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
Wan D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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