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Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | Q9UEW8 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 59kDa |
| Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
| Gene ID | 27347 |
|---|---|
| Other Names | STE20/SPS1-related proline-alanine-rich protein kinase, Ste-20-related kinase, 2.7.11.1, DCHT, Serine/threonine-protein kinase 39, STK39, SPAK |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | STK39 / SPAK Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | STK39 |
|---|---|
| Synonyms | SPAK |
| Function | May act as a mediator of stress-activated signals. Mediates the inhibiton of SLC4A4, SLC26A6 as well as CFTR activities by the WNK scaffolds, probably through phosphorylation. |
| Cellular Location | Cytoplasm. Nucleus. Note=Nucleus when caspase-cleaved. |
| Tissue Location | Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
May act as a mediator of stress-activated signals.
References
Johnston A.M.,et al.Oncogene 19:4290-4297(2000).
Corominas R.,et al.Nat. Commun. 5:3650-3650(2014).
Melnick M.B.,et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Baytel D.,et al.Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases.
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