STK39 / SPAK Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, IF, E |
---|---|
Primary Accession | Q9UEW8 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 59kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 27347 |
---|---|
Other Names | STE20/SPS1-related proline-alanine-rich protein kinase, Ste-20-related kinase, 2.7.11.1, DCHT, Serine/threonine-protein kinase 39, STK39, SPAK |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | STK39 / SPAK Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | STK39 |
---|---|
Synonyms | SPAK |
Function | May act as a mediator of stress-activated signals. Mediates the inhibiton of SLC4A4, SLC26A6 as well as CFTR activities by the WNK scaffolds, probably through phosphorylation. |
Cellular Location | Cytoplasm. Nucleus. Note=Nucleus when caspase-cleaved. |
Tissue Location | Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis |

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Background
May act as a mediator of stress-activated signals.
References
Johnston A.M.,et al.Oncogene 19:4290-4297(2000).
Corominas R.,et al.Nat. Commun. 5:3650-3650(2014).
Melnick M.B.,et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Baytel D.,et al.Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases.

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