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CLEC2D / OCIL / LLT1 Antibody (Internal)

Goat Polyclonal Antibody

     
  • IHC - CLEC2D / OCIL / LLT1 Antibody (Internal) ALS13098
    Anti-CLEC2D antibody IHC of human placenta.
  • IHC - CLEC2D / OCIL / LLT1 Antibody (Internal) ALS13098
    Anti-CLEC2D antibody IHC of human tonsil.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q9UHP7
Reactivity Human, Monkey, Horse
Host Goat
Clonality Polyclonal
Calculated MW 22kDa
Dilution ELISA (1:16000), IHC-P (3.75 µg/ml),
Additional Information
Gene ID 29121
Other Names C-type lectin domain family 2 member D, Lectin-like NK cell receptor, Lectin-like transcript 1, LLT-1, Osteoclast inhibitory lectin, CLEC2D, CLAX, LLT1, OCIL
Target/Specificity Human CLEC2D.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsCLEC2D / OCIL / LLT1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLEC2D
Synonyms CLAX, LLT1, OCIL
Function Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon- gamma. Binds high molecular weight sulfated glycosaminoglycans.
Cellular Location Cell membrane; Single-pass type II membrane protein. Cell surface Isoform 4: Endoplasmic reticulum.
Tissue Location Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells
Research Areas
Citations (0)

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Background

Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon- gamma. Binds high molecular weight sulfated glycosaminoglycans.

References

Boles K.S.,et al.Immunogenetics 50:1-7(1999).
Hu Y.S.,et al.J. Bone Miner. Res. 19:89-99(2004).
Germain C.,et al.J. Biol. Chem. 285:36207-36215(2010).
Yang G.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
Scherer S.E.,et al.Nature 440:346-351(2006).

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$ 395.00
Cat# ALS13098
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