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Fc Epsilon RI / FcERI Antibody (clone AER-37 (CRA1))

Mouse Monoclonal Antibody

     
  • IHC - Fc Epsilon RI / FcERI Antibody (clone AER-37 (CRA1)) ALS13121
    Anti-FCER1A antibody IHC of human mast cell in human small intestine.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, Flo
Primary Accession P12319
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names AER-37 (CRA1)
Calculated MW 30kDa
Dilution IHC-P (20 µg/ml)
Additional Information
Gene ID 2205
Other Names High affinity immunoglobulin epsilon receptor subunit alpha, Fc-epsilon RI-alpha, FcERI, IgE Fc receptor subunit alpha, FCER1A, FCE1A
Reconstitution & Storage Store at 4°C, avoid repeated freeze thaw cycles.
PrecautionsFc Epsilon RI / FcERI Antibody (clone AER-37 (CRA1)) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FCER1A
Synonyms FCE1A
Function Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Background

Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.

References

Kochan J.,et al.Nucleic Acids Res. 16:3584-3584(1988).
Shimizu A.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:1907-1911(1988).
Yagi S.,et al.Eur. J. Biochem. 220:593-598(1994).
Padlan E.A.,et al.Receptor 2:129-144(1992).
Garman S.C.,et al.Cell 95:951-961(1998).

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$ 395.00
Cat# ALS13121
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