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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   FAAH Antibody (C-Terminus)   

FAAH Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • IHC - FAAH Antibody (C-Terminus) ALS13180
    Anti-FAAH antibody IHC of human brain, cortex.
  • IHC - FAAH Antibody (C-Terminus) ALS13180
    Anti-FAAH antibody IHC of human testis.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession O00519
Reactivity Human, Monkey
Host Goat
Clonality Polyclonal
Calculated MW 63kDa
Dilution IHC-P (3.75 µg/ml)
Additional Information
Gene ID 2166
Other Names Fatty-acid amide hydrolase 1, 3.5.1.99, Anandamide amidohydrolase 1, Oleamide hydrolase 1, FAAH, FAAH1
Target/Specificity Human FAAH.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsFAAH Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FAAH
Synonyms FAAH1
Function Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates.
Cellular Location Endomembrane system; Single-pass membrane protein. Cytoplasm, cytoskeleton. Note=Seems to be attached to intracellular membranes and a portion of the cytoskeletal network
Tissue Location Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate
Research Areas
Citations (0)

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Background

Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates.

References

Giang D.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:2238-2242(1997).
Wan M.,et al.Genomics 54:408-414(1998).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).

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$ 395.00
Cat# ALS13180
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