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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CDC25C Antibody (clone 1F12)   

CDC25C Antibody (clone 1F12)

Mouse Monoclonal Antibody

     
  • IHC - CDC25C Antibody (clone 1F12) ALS13197
    Anti-CDC25C antibody IHC of human testis.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P30307
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1F12
Calculated MW 53kDa
Dilution IHC-P (1:200), WB (1:500-1:2000),
Additional Information
Gene ID 995
Other Names M-phase inducer phosphatase 3, 3.1.3.48, Dual specificity phosphatase Cdc25C, CDC25C
Target/Specificity Human CDC25C
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsCDC25C Antibody (clone 1F12) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDC25C
Function Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.
Cellular Location Nucleus
Research Areas
Citations (0)

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Background

Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.

References

Sadhu K.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:5139-5143(1990).
Bureik M.,et al.Int. J. Oncol. 17:1251-1258(2000).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Wegener S.,et al.Eur. J. Cell Biol. 79:810-815(2000).
Hernandez S.,et al.Lab. Invest. 81:465-473(2001).

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$ 395.00
Cat# ALS13197
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