CDC25C Antibody (clone 1F12)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P30307 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 1F12 |
Calculated MW | 53kDa |
Dilution | IHC-P (1:200), WB (1:500-1:2000), |
Gene ID | 995 |
---|---|
Other Names | M-phase inducer phosphatase 3, 3.1.3.48, Dual specificity phosphatase Cdc25C, CDC25C |
Target/Specificity | Human CDC25C |
Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | CDC25C Antibody (clone 1F12) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CDC25C |
---|---|
Function | Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle (PubMed:8119945). When phosphorylated, highly effective in activating G2 cells into prophase (PubMed:8119945). Directly dephosphorylates CDK1 and activates its kinase activity (PubMed:8119945). |
Cellular Location | Nucleus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.
References
Sadhu K.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:5139-5143(1990).
Bureik M.,et al.Int. J. Oncol. 17:1251-1258(2000).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Wegener S.,et al.Eur. J. Cell Biol. 79:810-815(2000).
Hernandez S.,et al.Lab. Invest. 81:465-473(2001).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.