FASN / Fatty Acid Synthase Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P49327 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 273kDa |
Dilution | IHC-P (3.75 µg/ml) |
Gene ID | 2194 |
---|---|
Other Names | Fatty acid synthase, 2.3.1.85, [Acyl-carrier-protein] S-acetyltransferase, 2.3.1.38, [Acyl-carrier-protein] S-malonyltransferase, 2.3.1.39, 3-oxoacyl-[acyl-carrier-protein] synthase, 2.3.1.41, 3-oxoacyl-[acyl-carrier-protein] reductase, 1.1.1.100, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, 4.2.1.59, Enoyl-[acyl-carrier-protein] reductase, 1.3.1.39, Oleoyl-[acyl-carrier-protein] hydrolase, 3.1.2.14, FASN, FAS |
Target/Specificity | Human FASN / Fatty Acid Synthase. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | FASN / Fatty Acid Synthase Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FASN |
---|---|
Synonyms | FAS |
Function | Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain. |
Cellular Location | Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV |
Tissue Location | Ubiquitous. Prominent expression in brain, lung, liver and mammary gland. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
References
Jayakumar A.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:8695-8699(1995).
Hennigar R.A.,et al.Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases.
Mao J.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Nakajima D.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Zody M.C.,et al.Nature 440:1045-1049(2006).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.