|Application ||WB, IHC-P, E|
|Dilution||IHC-P (1:200), WB (1:500-1:2000),|
|Other Names||Synaptophysin, Major synaptic vesicle protein p38, SYP|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SYP / Synaptophysin Antibody (clone 7H12) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome|
|Tissue Location||Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype|
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Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
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Oezcelik T.,et al.Am. J. Hum. Genet. 47:551-561(1990).
Fisher S.E.,et al.Genomics 45:340-347(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
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