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DAP-5 / EIF4G2 Antibody

Rabbit Polyclonal Antibody

     
  • WB - DAP-5 / EIF4G2 Antibody ALS13241
    Sample(30 g of whole cell lysate). A: A431. 7.5% SDS PAGE. EIF4G2 antibody diluted at 1:1000.
  • IHC - DAP-5 / EIF4G2 Antibody ALS13241
    Anti-EIF4G2 antibody IHC of human adrenal.
  • IHC - DAP-5 / EIF4G2 Antibody ALS13241
    Anti-EIF4G2 antibody IHC of human skeletal muscle.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P78344
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 102kDa
Dilution IHC-P (10 µg/ml), WB (1:500-1:3000),
Additional Information
Gene ID 1982
Other Names Eukaryotic translation initiation factor 4 gamma 2, eIF-4-gamma 2, eIF-4G 2, eIF4G 2, Death-associated protein 5, DAP-5, p97, EIF4G2 (HGNC:3297)
Target/Specificity Human EIF4G2. Predicted cross-reactivity based on amino acid sequence homology: mouse (100%), rat (100%), rabbit (100%), bovine (100%), zebrafish (82%).
Reconstitution & Storage Aliquot and store at -20°C. Minimize freezing and thawing.
PrecautionsDAP-5 / EIF4G2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EIF4G2 (HGNC:3297)
Function Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.
Tissue Location Ubiquitously expressed in all adult tissues examined, with high levels in skeletal muscle and heart. Also expressed in fetal brain, lung, liver and kidney
Volume 50 µl
Research Areas
Citations (0)

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Background

Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.

References

Imataka H.,et al.EMBO J. 16:817-825(1997).
Yamanaka S.,et al.Genes Dev. 11:321-333(1997).
Levy-Strumpf N.,et al.Mol. Cell. Biol. 17:1615-1625(1997).
Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Taylor T.D.,et al.Nature 440:497-500(2006).

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$ 395.00
Cat# ALS13241
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