|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml), WB (1:500-1:3000),|
|Other Names||2', 3'-cyclic-nucleotide 3'-phosphodiesterase, CNP, CNPase, 220.127.116.11, CNP|
|Target/Specificity||Human CNP. Predicted cross-reactivity based on amino acid sequence homology: mouse (82%), rat (84%), bovine (89%), monkey (97%).|
|Reconstitution & Storage||Aliquot and store at -20°C. Minimize freezing and thawing.|
|Precautions||CNP / CNPase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.|
|Cellular Location||Membrane; Lipid-anchor. Melanosome. Note=Firmly bound to membrane structures of brain white matter Identified by mass spectrometry in melanosome fractions from stage I to stage IV|
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Provided below are standard protocols that you may find useful for product applications.
May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
Thompson R.J.,et al.Biochem. Soc. Trans. 20:621-626(1992).
Kurihara T.,et al.Biochem. Biophys. Res. Commun. 152:837-842(1988).
Monoh K.,et al.Gene 129:297-301(1993).
Douglas A.J.,et al.Ann. Hum. Genet. 56:243-254(1992).
Zody M.C.,et al.Nature 440:1045-1049(2006).
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